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Implementation of a multifaceted antimicrobial stewardship program (ASP) in a large community hospital in New Jersey was associated with significant, sustained reductions in unnecessary antibiotic use, Clostridioides difficile infection (CDI) rates, and antimicrobial acquisition costs, researchers reported late last week in Infection Control & Hospital Epidemiology.
Early treatment with molnupiravir nearly halved the risk of hospitalization and death.
New UK estimations cast doubt on whether Omicron cases are less severe than Delta variant infections.
Test to Stay involves testing close contacts of a COVID-19 student at least twice in the week after exposure.
Key antibiotic sales for food animals fell just 3% from 2019 to 2020, and the decline has plateaued.
COVID-19 breakthrough infections in fully vaccinated US adults substantially boosted humoral immunity and demonstrated cross-neutralization against the Delta (B1617.2) variant, despite mostly mild illness, finds a small study yesterday in JAMA.
Humoral immunity involves antibodies secreted by B cells circulating in bodily fluids.
A randomized trial involving more than 8,000 children in low-income settings found that azithromycin did not improve mortality in children with acute diarrhea, an international team of researchers reported yesterday in JAMA Network Open.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
The vaccine can be stored for up to 6 months at refrigerator temperatures.
ACIP votes unanimously that mRNA vaccines are preferred over the Johnson & Johnson vaccine for US adults.
Of Denmark's Omicron patients, 75% were fully vaccinated, and 9% had received a booster shot.
Only 20% and 24% of Pfizer/BioNTech COVID-19 vaccine recipients in a Chinese study had detectable neutralizing antibodies against two isolates of the highly transmissible Omicron (B.1.1.529) variant, while recipients of the Coronavac vaccine had no antibodies against either isolate.
The Democratic Republic of the Congo (DRC) today declared the end of its thirteenth Ebola outbreak, given that two 21-day incubation periods have passed since the last patient was discharged from treatment, the World Health Organization (WHO) African regional office said today.
One study finds that 2 doses of Moderna were highly effective against all variants, but Delta protection waned.
The virus multiplies 70 times faster in the bronchi than Delta and the original SARS-CoV-2, researchers report.
About half of the deaths have occurred in the past year, when vaccines have been available.
Finance ministers for G7 countries yesterday issued a statement in support of actions to boost development of new antibiotics.
Researchers updated a Commonwealth Fund study yesterday, and now estimate that COVID-19 vaccination has prevented 1.1 million US deaths and 10.3 million hospitalizations, up from July's figure of 279,000 deaths and 1.25 million hospitalizations prevented.
Those staying in hotel rooms with medical and social support fared better than those in a shelter.
Even if Omicron causes less severe disease, sheer numbers could overwhelm hospitals.
