Researchers report that a high dose of a novel oral microbiome-directed therapy prevented recurrent Clostridioides difficile infection.
The drug combines sulbactam with a novel, broad-spectrum beta-lactamase inhibitor and targets Acinetobacter baumannii-calcoaceticus complex.
The trial found perioperative use of piperacillin-tazobactam significantly reduced surgical-site infections.
The open-source statistical code uses electronic health record data to assess antibiotic prescribing.
Scientists from Africa, Asia, Europe, and South America are forming a research network that will address the major drivers of antimicrobial resistance.
New data show that that 78% of compassionate-use bacteriophage treatments given to patients since 2018 have resulted in a favorable outcome.
All isolates were resistant to at least one antibiotic, with the vast majority of Salmonella and Shigella isolates resistant to trimethoprim-sulfamethoxazole.
Nearly two thirds of antibiotics dispensed in community pharmacies around the world are given without a prescription.
Scientists are looking to gain a better understanding of the prevalence of antibiotic-resistant bacteria in the general population.
Medium-to-very-high expectation scores were associated with higher levels of satisfaction upon receiving antibiotics.
The PASTEUR was introduced in 2020 and 2021 but never received a vote despite bipartisan support.
The drug marks the first fecal microbiota therapy that can be taken orally.
The recipients are Vedanta Biosciences, whose lead candidate is a microbiome-directed C difficile therapy, and diagnostics company Pattern Bioscience for rapid bacterial susceptibility tests.
The hospital says it's unclear whether the K pneumoniae infections caused or contributed to the 7 patient deaths.
Shortages of some drugs to treat kids' respiratory illnesses come amid surges of RSV and the flu and continuing COVID-19.
During shortages of 5 antibiotics at a US children's hospital, prescribers adhered to restriction protocols 57% of the time.
Despite the milestone, funding remains far short of what's needed, according to a new report.
A trial in Ethiopia suggests mass azithromycin distribution to wide, contiguous areas may reduce the likelihood of the infection that causes trachoma.
Hospitals with the highest prevalence of highly resistant microorganisms instituted the fewest infection prevention and control measures.
Previous research in Bangladesh has suggested that exposure to arsenic might play a role in the emergence and spread of antibiotic resistance.
A study of 4 VA hospitals finds that almost a third of urinary tract infection diagnoses are inappropriate in patients with neurogenic bladder.
The Taiwan Food and Drug Administration will review Shionogi's NDA for the novel antibiotic.
The findings also call into question the idea that improving knowledge of antibiotics can improve antibiotic use, the study authors say.
At least 5 European countries are reporting an increase in invasive group A Streptococcus disease and scarlet fever.
Report spotlights concerning levels of resistance to several antibiotics.
