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CARB-X announced today that it is awarding up to $2.62 million to Swiss biopharmaceutical company Polyphor AG to develop a new antibiotic to treat infections caused by Enterobacteriaceae, including carbapenem-resistant Enterobacteriaceae (CRE).
In one of the first large-scale studies of COVID-19 transmission in US childcare programs, no association was found between day care exposure and COVID-19 transmission risk for providers.
Two studies show the new antibiotic is safe and effective for difficult-to-treat MDR infections.
Only 2 of 101 newborns had positive COVID-19 test results, but they had no signs or symptoms.
Both a vaccine trial and monoclonal antibody trial have been paused.
The first SARS-CoV-2 infections in US animals were confirmed in large cats at the Bronx Zoo in March during the height of the local COVID-19 outbreak. An American Society for Microbiology study today details the genomic characteristics of viruses that infected zookeepers, four tigers, and three African lions, supporting a human-to-animal transmission pathway.
A group led by the African Commission through the Africa Centres for Disease Control and Prevention (Africa CDC), yesterday launched the Africa Pathogen Genomics Initiative (Africa PGI), a $100 million, 4-year partnership to expand and integrate next-generation genomic sequencing (NGS) capabilities across the continent to improve health surveillance and lab networks and better tackle antimicrobial resistance (AMR).
The report contains coordinated actions aimed at changing the trajectory of antibiotic resistance.
The data offer hope for disease protection, but persistence was not analyzed beyond 4 months.
Since May 10, the US rate has exceeded that of all other nations studied.
The vast majority of the world is still susceptible to the virus, the WHO director says.
A trio of studies look at young adults' actions and consequences during the pandemic.
The US Food and Drug Administration (FDA) late last week published a concept paper outlining potential revisions to criteria that the agency uses to guide the use of medically important antimicrobial drugs in veterinary medicine.
A study late last week found that convalescent plasma (CP) treatment did not significantly reduce mortality, but improved hospital discharge rates for patients 65 and older. The study in Clinical Infectious Diseases is one of the first to analyze clinical outcomes for closely matched cohorts of CP and control patients.
In 2000, Europe imported 31% of drug materials from Asia; the number has now grown to 63%.
Studies find that women, older people, and the conscientious tended to adhere better.
Remdesivir helped patients recover faster, but hydroxychloroquine, again, did not prevent death.
Cases are rising in 28 states, and details on Trump's illness are still murky.
Several European nations report new daily highs, and hospital cases are rising in France.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
Originally published by CIDRAP News Oct 7
European lawmakers yesterday called for the European Union (EU) to address antibiotic shortages and antibiotic development as key components of its forthcoming Pharmaceutical Strategy for Europe.
