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Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
Originally published by CIDRAP News Oct 22
Sales of veterinary antibiotics in European countries fell by more than one-third from 2011 through 2018, according to a report yesterday from the European Medicines Agency (EMA).
Ten countries reported a total of 87 new polio cases over the past week, including Afghanistan and Pakistan seven African nations, and Yemen, according to the latest update from the Global Polio Eradication Initiative (GPEI).
In the first large study looking at SARS-CoV-2 viral loads (VL) in asymptomatic children, researchers found that VL were 3 to 4 logs lower compared with symptomatic children, which was consistent with the difference in median cycle threshold (Ct) values—10.3 cycles—between the two groups.
Gilead says the approval is based on results of 3 randomized controlled trials.
The study also found that those with Down syndrome had 5 times the risk of hospitalization.
A paper published yesterday in the Morbidity and Mortality Weekly Report highlights a case study the Centers for Disease Control and Prevention (CDC) has used to update how it defines close contacts of people infected with SARS-CoV-2, the virus that causes COVID-19.
The past week has seen nearly 60,000 US cases a day on average and 700 deaths.
Trust in institutions and leaders seems to affect how likely people will be to accept COVID-19 vaccination.
And US officials might be missing almost 200,000 COVID-19 deaths.
Experts call for a move from a "fail and fix" approach to a "predict and prevent" paradigm.
If a new bill is passed, Congress would provide $11 billion over 10 years to support antibiotic development.
A study yesterday in Infection Control & Hospital Epidemiology found that individuals with mild or no COVID-19 symptoms may be infectious for no more than about 10 days, while those with severe illness may be able to spread the virus for as long as 20 days. The infectious periods align with US Centers for Disease Control and Prevention (CDC) recommendations for isolation time.
Today CARB-X announced it is funding $3.94 million to Cellics Therapeutics, based in San Diego, to further its nanomedicine treatment for sepsis.
A large observational study showed some promise, but 2 randomized clinical trials did not.
"The message is be prepared for a bad flu season on top of a bad COVID season," says Edward Belongia, MD.
The CDC now recommends mask wearing on airplanes, trains, subways, buses, taxis, and other ride-share vehicles.
Data from inpatient Veterans Administration (VA) hospitals show a significant increase in antibiotic use from January to May, largely negating a downward trend over the previous 5 years, researchers reported today in Infection Control and Hospital Epidemiology.
Racial and ethnic minority workers have been disproportionately affected by COVID-19 in food manufacturing and agriculture workplaces, according to a study yesterday in Emerging Infectious Diseases.
Demographics were not available for all 742 sites surveyed across 30 states, but for those that were, 83.2% of confirmed cases involved minorities even though they made up only 47.4% of all workers.
The death rate was high in patients with chronic kidney disease and in those who developed kidney injury in the ICU.
