Analysis suggests cigarette butts are a source of antibiotic-resistance genes

News brief

Cigarette butts in grass — Olga Ihnatsyeva / iStock

A new study suggests cigarette butts are an "overlooked yet potent" source of antibiotic resistance genes (ARGs), Chinese researchers reported today in the Proceedings of the National Academy of Sciences.

For the study, scientists from the Chinese Academy of Sciences collected cigarette butts, plant litter, and soil from 105 urban green spaces and 35 cities across China and analyzed them for the presence of ARGs and bacterial pathogens using shotgun metagenomic sequencing. They were interested in studying cigarette butts because they come into direct contact with the opportunistic and pathogenic bacteria within the smoker's oral cavity, are ubiquitous in the environment, and contain substances that can leach into the environment.

"Urban greenspaces are key recreational areas for picnicking, exercise, and children's activities, yet they are frequently contaminated with discarded cigarette butts," the study authors wrote. "We hypothesize that cigarette butts create a favorable niche for the proliferation and persistence of ARGs and potential pathogens due to their unique combination of human-derived microbiota and chemical contaminants."

Human-associated waste as a source of ARGs

In total, 1,356 ARG subtypes spanning 29 antibiotic-resistance classes were identified, with 1,209 occurring in cigarette butts. The abundance of ARGs in cigarette butts was 1.24-fold higher than in plant litter and 1.48-fold higher than in soil, and also exceeded ARG levels found on other artificial surfaces, such as buildings. The researchers detected 95 potential pathogens in cigarette butts, which was twice as many as they found in plant litter and three times as many as in soil. Clinically relevant, ARG-enriched pathogens in cigarette butts included Enterobacter, Escherichia coli, and Pseudomonas.

Further analysis found that socioeconomic factors, including lower Gross Domestic Product, poorer education, larger smoking populations, and inadequate waste management were strongly linked to elevated health risks from ARGs and potential pathogens in cigarette butts.

"Together, our findings underscore the need to recognize human-associated waste as a vector of ARGs and to integrate cigarette waste into urban health management within the One Health framework," the authors concluded.

First West Nile death of 2025 confirmed in LA County

News brief

Stephanie Soucheray, MA

The Los Angeles County Department of Public Health late last week confirmed the first West Nile Virus death of the year in a resident of San Fernando Valley, who was hospitalized and died from neurologic illness following a severe West Nile virus infection.

This tragic loss reminds us how dangerous mosquito-borne diseases like West Nile virus and dengue can be.

“This tragic loss reminds us how dangerous mosquito-borne diseases like West Nile virus and dengue can be,” said Muntu Davis, MD, MPH, Los Angeles County Health Officer in a press release. “Protect yourself and your neighbors by using insect repellent, getting rid of standing water where mosquitoes breed, and keeping window and door screens in good repair. Small actions like these can make a big difference in preventing illness.”

So far this year Los Angeles County has documented 14 West Nile virus cases, with half coming from the San Fernando Valley region.

According to county officials, peak mosquito season lasts from June to November in Los Angeles County. Most people infected with the virus don't have symptoms, but about 1 in 5 develop a fever and other symptoms such as headache, body aches, joint pain, and vomiting. About 1 in 150 of those infected will have severe symptoms that may include high fever, stiff neck, muscle weakness, and sometimes a rash.

Avian Flu detected on more Minnesota turkey farms

News brief

Stephanie Soucheray, MA

Over the weekend the US Department of Agriculture's Animal and Plant Health Inspection Service (APHIS) reported more detections of highly pathogenic avian influenza (HPAI) in commercial and backyard poultry flocks.

Notably, two large commercial turkey farms were hit in Minnesota, the nation's top turkey producer and the current epicenter of HPAI activity. A commercial turkey farm was affected in Meeker County with 132,500 birds reported avian flu, as was a producer in Otter Tail County with 36,900 birds.

Broiler farm in Georgia also affected

A commercial broiler chicken facility in Georgia's Gordon County also reported avian flu, affecting 139,000 birds.

Infected backyard flocks in Montana and Michigan were also reported. And three farms had confirmed HPAI in Lancaster County, Pennsylvania, which has had several recent detections. The flocks ranged in size from 1,000 to 45,900 poultry.

Avian flu activity is increasing across the country. In the past 30 days, confirmations have been made in 64 flocks, including 30 commercial flocks and 34 backyard flocks, with 3.57 million birds affected in the outbreaks.

Minnesota has seen the highest jump in activity, with 665,720 birds affected.