At eight months of follow-up, Jynneos recipients not vaccinated against smallpox had lower binding antibody concentrations than those with infection.
The test the US Centers for Disease Control and Prevention uses to identify clade I mpox cases is 'most likely not reliable' for detection of the substrain identified in the study, the authors say.
Another mpox study today showed that dose-sparing vaccine administration of the Jynneos vaccine appeared to have worked.
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Though given to only 1 patient, tecovirimat was tied to a shorter illness and signs of shorter viral shedding.
Cases in Europe have risen to 118, and the UK has now confirmed 78 monkeypox infections.
California and Washington state report their first cases, as CDC experts advise on what doctors should be alert for.
The CDC says many patients have a distinctive monkeypox rash around their genitals, and UK officials report 36 new infections.
At least 8 European countries and Canada, the US, and Australia have tallied cases.
As cases climb in several nations, an expert notes, "We are much more susceptible to poxviruses."
UK cases grow to 9, while Spain reports 23 suspected cases and Portugal 5 confirmed, 15 suspected.
Machine-learning models created by a National Institutes of Health (NIH)-supported research team can identify, with high accuracy, patients likely to have long COVID, according to a study yesterday in The Lancet Digital Health.
A randomized, controlled trial of 400 adults hospitalized for COVID-19–related respiratory failure suggests that awake prone positioning doesn't significantly reduce the need for endotracheal intubation at 30 days, but the authors caution that the effect size was imprecise and a therapeutic benefit cannot be ruled out.
In a study published in Open Forum Infectious Diseases, researchers showed canine olfaction—or dog sniffing—was both highly sensitive and specific when it came to identifying patients with COVID-19, even those who were asymptomatic or presymptomatic.
