Analysis of Neisseria gonorrhoeae isolates from 3 African countries finds high resistance to ciprofloxacin and emerging resistance determinants for azithromycin.
The pooled proportion of cases treated successfully was 44%, well below the WHO target success rate of 75%.
Priorities include improving access to new and existing antibiotics, diagnostics, and antibiotic alternatives.
The designation means that the NgG vaccine, which is in a phase 2 trial, will receive expedited review by FDA officials.
Antibiotics significantly reduced bacterial diversity and altered the gut microbiome of infants in low- and middle-income countries.
A single-center study in Canada finds a low incidence of bacterial infections in infants with viral infections, including SARS-CoV-2.
The agenda highlights 5 themes: transmission, integrated surveillance, interventions, behavioral insights and change, and economics and policy.
The Bill & Melinda Gates Foundation and Wellcome will provide $550 million for a phase 3 trial of a vaccine to prevent tuberculosis.
The results track with earlier findings regarding disease burden, but the mechanisms behind the association need to be fleshed out.
A lack of access to medical treatment and lack of knowledge about antibiotic resistance may influence getting antibiotics from unqualified sources.
Abundance of antibiotic resistance genes was highest in Africa and second highest in Southeast Asia.
The first clinical trial of a 3-month treatment regimen for tuberculosis is closing enrollment because of a high rate of unfavorable outcomes.
Infectious disease consultation was associated with a 40% reduced risk of death.
Antibiotic use, invasive devices, and several days of hospitalization were significantly associated with carriage of multidrug-resistant bacteria.
Whole-genome sequencing identified an array of antibiotic resistance genes, including multiple carbapenemase and extended-spectrum beta-lactamase genes.
Data from hospitals in Chile, Brazil, and Argentina show substantial increases in intravenous antibiotic use at the beginning of the pandemic.
The researchers observed a dose-response relationship between the number of antibiotic prescriptions and risk of severe outcomes.
Lumos Diagnostics receives FDA clearance for a test that helps to determine when antibiotics are needed for respiratory infections.
A total of 149 oral antibiotic prescriptions were reviewed, and 55 interventions were made, 42 of which were accepted.
Inappropriate antibiotic prescriptions to prevent infective endocarditis cost the system nearly $31 million a year, according to new research.
With the proposed expansion of the program, annual contracts could double to £20 million (US $25.9 million).
The $20.5 million base funding will support plans to extend Baxdela's pneumonia indication and Vabomere's use for complicated urinary tract infections to children.
A third of late-onset sepsis cases in very-low-birthweight infants were caused by multidrug-resistant organisms, 41% of which proved fatal.
The funds are part of an effort to help officials track antimicrobial resistance patterns and detect emerging resistance profiles.
Key factors associated with antibiotic resistance rates varied greatly among drug-bacterium pairs.
