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Repeat SARS-CoV-2 infections confer significant additional risk of adverse multi-organ medical conditions and poor outcomes such as hospitalization, diabetes, kidney disease, mental illness, death, and diseases affecting the lungs, heart, brain, blood, and musculoskeletal systems, suggests a study published yesterday in Nature Medicine.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
A study of 97 hospitals in the United States and Canada found that the incidence of urinary tract infection (UTI) and invasive bacterial infection (IBI) in infants with fever fell to pre-pandemic levels by early 2022, researchers reported yesterday in Pediatrics.
Some European firms are closing or scaling back operations, fueling fears of shortages of essential drugs.
Weekly COVID-19 hospitalizations of infants younger than 6 months rose 11-fold from April to July 2022.
Kids were 30% more likely than controls to have symptoms 3 month or more after COVID-19.
JAMA Network Open published a new study yesterday showing higher cord blood COVID-19 antibodies in women who were vaccinated compared with those who were infected with COVID-19, suggesting vaccination produces more than 10-fold higher antibody concentrations in unborn babies compared to natural infections.
A study of more than 3 million patients with bacterial and viral respiratory infections found that inappropriate antibiotic prescriptions were associated with increased risk of adverse events and higher healthcare costs, researchers reported today in Clinical Infectious Diseases.
Southeast Asia and the Western Pacific saw modest rises, but cases are down worldwide.
Study reveals disparities in access to sites—and thus antivirals—with 15% living more than an hour away.
At a World Health Organization (WHO) briefing today, Director-General Tedros Adhanom Ghebreyesus, PhD, said Uganda's government is making progress in its battle against Ebola, but he raised concerns about case detections outside the main hot spots.
An observational study published this week in eClinicalMedicine suggests that COVID-19–related acute kidney injury (AKI) is tied to a greater risk of death, and that severe AKI may lead to poor recovery of kidney function.
Myocarditis and pericarditis are rare after COVID vaccination, but rates were twofold to threefold higher after receipt of the second dose of the Moderna vaccine than after the Pfizer version.
A study of US patients aged 0 to 20 years hospitalized for COVID-19 or multisystem inflammatory syndrome in children (MIS-C) in 2020 and 2021 shows that 22% had a neurologic condition, including 9% with life-threatening illness.
A clinical trial conducted in seven countries found that two shortened, bedaquiline-containing regimens had superior efficacy in treating rifampicin-resistant tuberculosis (TB) compared with a 9-month injectable-containing regimen, with fewer cases of hearing loss, investigators reported today in The Lancet.
Those taking Paxlovid had a 25% lower risk of developing 10 of 12 long-COVID conditions.
With Arizona, Mississippi, and South Carolina now affected, poultry losses will soon set a record.
Selective serotonin reuptake inhibitors (SSRIs), the most commonly used class of antidepressants in the United States, don't appear to prevent severe COVID-19 or death among outpatients, according to a study presented this week at the American Heart Association's Scientific Sessions in Chicago.
A study of electronic health record (EHR) data from a US hospital network found that more than a third of antibiotic prescriptions for uncomplicated urinary tract infections (uUTIs) were inappropriate or suboptimal, researchers reported late last week in Antimicrobial Resistance and Infection Control.
Muliple respiratory viruses are already straining health systems, with children among the hardest hit groups.
Black children made up 47% of the 83 pediatric patients, with Latinos making up 35%.
